PAT School – NIR for blending monitoring

 In various manufacturing sectors, the blending process is of utmost importance, and achieving optimisation necessitates a profound understanding of the procedure to guarantee uniform blending of the end product. The act of sampling using a “thief” introduces substantial process disruptions, prompting the FDA to advocate strongly for a transition from process validation to continuous process verification.

Participating in the workshop will enhance your understanding of both the theoretical and practical aspects of NIR for monitoring blending processes.

Topics will include: 

• • NIR theory
  • Design of experiments
  • Principal Component Analysis and Moving Block Averaging
  • Basic software operations
  • Blending Scale-up : Lab → Pilot → Production
  • Blending a ‘Golden Batch’ every time
  • Realtime measurements
  • Audit trail compliance and regulatory clarification
  • OPC UA and process integration